Process Analytical Technology (PAT) is a mechanism to design, analyze, and control pharmaceutical manufacturing processes through the measurement of critical process parameter. Common technologies are Raman and FT-IR spectroscopy, which acquire time based 2 dimensional spectra that are stored as flat files or in SQL databases. At Cognizant life science manufacturing we created a commercial solution to collect, analyze and display PAT spectra within the PI System. The solution is currently being deployed at a major pharmaceutical company. To achieve this, we extended the PI System to:

• Store multi-dimensional time series
• Analyze PAT in AF System Explorer or in a PI Vision symbol
• Display PAT spectra next to traditional process data in PI Vision
• Allow batch relative displays of PAT data

The goal is to make PAT information accessible to researcher and production operator, accelerate development and improve product quality.